代表论文目录   

01: Wang LD, Lipkin M, Qui SL, Yang GR, Yang CS, Newmark HL. Related Articles, Links
Labeling index and labeling distribution of cells in esophageal epithelium of individuals at increased risk for esophageal cancer in Huixian, China.
Cancer Res. 1990 May 1;50(9):2651-3.
PMID: 2328490 [PubMed - indexed for MEDLINE]
02: Wang LD. Related Articles, Links
[Effect of added dietary calcium on human esophageal precancerous lesion in the high risk area for esophageal cancer--a randomized double blind intervention trial]
Zhonghua Zhong Liu Za Zhi. 1990 Sep;12(5):332-5. Chinese.
PMID: 2276321 [PubMed - indexed for MEDLINE]
03: Wang LD. Related Articles, Links
[Preliminary study on nutrition and precancerous lesions of the esophagus in the adolescents]
Zhonghua Zhong Liu Za Zhi. 1992 Mar;14(2):94-7. Chinese.
PMID: 1618089 [PubMed - indexed for MEDLINE]
04: Wang LD, Qiu SL, Yang GR, Lipkin M, Newmark HL, Yang CS. Related Articles, Links
A randomized double-blind intervention study on the effect of calcium supplementation on esophageal precancerous lesions in a high-risk population in China.
Cancer Epidemiol Biomarkers Prev. 1993 Jan-Feb;2(1):71-8.
PMID: 8420615 [PubMed - indexed for MEDLINE]
05: Wang LD, Hong JY, Qiu SL, Gao H, Yang CS. Related Articles, Links
Accumulation of p53 protein in human esophageal precancerous lesions: a possible early biomarker for carcinogenesis.
Cancer Res. 1993 Apr 15;53(8):1783-7.
PMID: 8467496 [PubMed - indexed for MEDLINE]
06: Gao H, Wang LD, Zhou Q, Hong JY, Huang TY, Yang CS. Related Articles, Links
p53 tumor suppressor gene mutation in early esophageal precancerous lesions and carcinoma among high-risk populations in Henan, China.
Cancer Res. 1994 Aug 15;54(16):4342-6.
PMID: 8044781 [PubMed - indexed for MEDLINE]
07: Wang LD, Shi ST, Zhou Q, Goldstein S, Hong JY, Shao P, Qiu SL, Yang CS. Related Articles, Links
Changes in p53 and cyclin D1 protein levels and cell proliferation in different stages of human esophageal and gastric-cardia carcinogenesis.
Int J Cancer. 1994 Nov 15;59(4):514-9.
PMID: 7960222 [PubMed - indexed for MEDLINE]
08: Wang ZY, Wang LD, Lee MJ, Ho CT, Huang MT, Conney AH, Yang CS. Related Articles, Links
Inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in rats by green and black tea.
Carcinogenesis. 1995 Sep;16(9):2143-8.
PMID: 7554067 [PubMed - indexed for MEDLINE]
09: Wang LD, Zhou Q, Hong JY, Qiu SL, Yang CS. Related Articles, Links
p53 protein accumulation and gene mutations in multifocal esophageal precancerous lesions from symptom free subjects in a high incidence area for esophageal carcinoma in Henan, China.
Cancer. 1996 Apr 1;77(7):1244-9.
PMID: 8608498 [PubMed - indexed for MEDLINE]
10: Wang LD, Zhou Q, Gou RY, Xing Y, Zhang BC, Li QJ, Yang CS. Related Articles, Links
Reproducibility of an esophageal biopsy sampling procedure in a high-incidence area for esophageal cancer in northern China.
Cancer Epidemiol Biomarkers Prev. 1996 May;5(5):405-6.
PMID: 9162308 [PubMed - indexed for MEDLINE]
11: Shi ST, Feng B, Yang GY, Wang LD, Yang CS. Related Articles, Links
Immunohistoselective sequencing (IHSS) of p53 tumor suppressor gene in human oesophageal precancerous lesions.
Carcinogenesis. 1996 Oct;17(10):2131-6.
PMID: 8895479 [PubMed - indexed for MEDLINE]
12: Wang LD, Zhou Q, Yang CS. Related Articles, Links
Esophageal and gastric cardia epithelial cell proliferation in northern Chinese subjects living in a high-incidence area.
J Cell Biochem Suppl. 1997;28-29:159-65.
PMID: 9589362 [PubMed - indexed for MEDLINE]
13: Smith TJ, Liao A, Wang LD, Yang GY, Starcic S, Philbert MA, Yang CS. Related Articles, Links
Characterization of xenobiotic-metabolizing enzymes and nitrosamine metabolism in the human esophagus.
Carcinogenesis. 1998 Apr;19(4):667-72.
PMID: 9600353 [PubMed - indexed for MEDLINE]
14: Yu GQ, Zhou Q, Ivan D, Gao SS, Zheng ZY, Zou JX, Li YX, Wang LD. Related Articles, Links
Changes of p53 protein blood level in esophageal cancer patients and normal subjects from a high incidence area in Henan, China.
World J Gastroenterol. 1998 Aug;4(4):365-366. No abstract available.
PMID: 11819322 [PubMed - as supplied by publisher]
15: Gao SS, Zhou Q, Li YX, Bai YM, Zheng ZY, Zou JX, Liu G, Fan ZM, Qi YJ, Zhao X, Wang LD. Related Articles, Links
Comparative studies on epithelial lesions at gastric cardia and pyloric antrum in subjects from a high incidence area for esophageal cancer in Henan, China.
World J Gastroenterol. 1998 Aug;4(4):332-333.
PMID: 11819313 [PubMed - as supplied by publisher]
16: Wang LD, Zhou Q, Wei JP, Yang WC, Zhao X, Wang LX, Zou JX, Gao SS, Li YX, Yang C. Related Articles, Links
Apoptosis and its relationship with cell proliferation, p53, Waf1p21, bcl-2 and c-myc in esophageal carcinogenesis studied with a high-risk population in northern China.
World J Gastroenterol. 1998 Aug;4(4):287-293.
PMID: 11819301 [PubMed - as supplied by publisher]
17: Xing EP, Nie Y, Wang LD, Yang GY, Yang CS. Related Articles, Links
Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China.
Carcinogenesis. 1999 Jan;20(1):77-84.
PMID: 9934853 [PubMed - indexed for MEDLINE]
18: Wang LD, Zhou Q, Yang WC, Yang CS. Related Articles, Links
Apoptosis and cell proliferation in esophageal precancerous and cancerous lesions: study of a high-risk population in northern China.
Anticancer Res. 1999 Jan-Feb;19(1A):369-74.
PMID: 10226569 [PubMed - indexed for MEDLINE]
19: Deng C, Xie D, Capasso H, Zhao Y, Wang LD, Hong JY. Related Articles, Links
Genetic polymorphism of human O6-alkylguanine-DNA alkyltransferase: identification of a missense variation in the active site region.
Pharmacogenetics. 1999 Feb;9(1):81-7.
PMID: 10208646 [PubMed - indexed for MEDLINE]
20: Shi ST, Yang GY, Wang LD, Xue Z, Feng B, Ding W, Xing EP, Yang CS. Related Articles, Links
Role of p53 gene mutations in human esophageal carcinogenesis: results from immunohistochemical and mutation analyses of carcinomas and nearby non-cancerous lesions.
Carcinogenesis. 1999 Apr;20(4):591-7.
PMID: 10223186 [PubMed - indexed for MEDLINE]
21: Xing EP, Yang GY, Wang LD, Shi ST, Yang CS. Related Articles, Links
Loss of heterozygosity of the Rb gene correlates with pRb protein expression and associates with p53 alteration in human esophageal cancer.
Clin Cancer Res. 1999 May;5(5):1231-40.
PMID: 10353761 [PubMed - indexed for MEDLINE]
22: Xing EP, Nie Y, Song Y, Yang GY, Cai YC, Wang LD, Yang CS. Related Articles, Links
Mechanisms of inactivation of p14ARF, p15INK4b, and p16INK4a genes in human esophageal squamous cell carcinoma.
Clin Cancer Res. 1999 Oct;5(10):2704-13.
PMID: 10537333 [PubMed - indexed for MEDLINE]
23: Cai YC, Yang GY, Nie Y, Wang LD, Zhao X, Song YL, Seril DN, Liao J, Xing EP, Yang CS. Related Articles, Links
Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53.
Carcinogenesis. 2000 Apr;21(4):683-9.
PMID: 10753204 [PubMed - indexed for MEDLINE]
24: Li J, Feng CW, Zhao ZG, Zhou Q, Wang LD. Related Articles, Links
A preliminary study on ras protein expression in human esophageal cancer and precancerous lesions.
World J Gastroenterol. 2000 Apr;6(2):278-280. No abstract available.
PMID: 11819576 [PubMed - as supplied by publisher]
25: Nie Y, Yang G, Song Y, Zhao X, So C, Liao J, Wang LD, Yang CS. Related Articles, Links
DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas.
Carcinogenesis. 2001 Oct;22(10):1615-23.
PMID: 11577000 [PubMed - indexed for MEDLINE]
26: Wang LD, Zhou Q, Feng CW, Liu B, Qi YJ, Zhang YR, Gao SS, Fan ZM, Zhou Y, Yang CS, Wei JP, Zheng S. Related Articles, Links
Intervention and follow-up on human esophageal precancerous lesions in Henan, northern China, a high-incidence area for esophageal cancer.
Gan To Kagaku Ryoho. 2002 Feb;29 Suppl 1:159-72.
PMID: 11890101 [PubMed - indexed for MEDLINE]
27: Feng CW, Wang LD, Jiao LH, Liu B, Zheng S, Xie XJ. Related Articles, Links
Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical features.
BMC Cancer. 2002 Apr 29;2(1):8.
PMID: 11978184 [PubMed - indexed for MEDLINE]
28: Zhou Y, Gao SS, Li YX, Fan ZM, Zhao X, Qi YJ, Wei JP, Zou JX, Liu G, Jiao LH, Bai YM, Wang LD. Related Articles, Links
Tumor suppressor gene p16 and Rb expression in gastric cardia precancerous lesions from subjects at a high incidence area in northern China.
World J Gastroenterol. 2002 Jun;8(3):423-5.
PMID: 12046062 [PubMed - indexed for MEDLINE]
29: Nie Y, Liao J, Zhao X, Song Y, Yang GY, Wang LD, Yang CS. Related Articles, Links
Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma.
Carcinogenesis. 2002 Oct;23(10):1713-20.
PMID: 12376481 [PubMed - indexed for MEDLINE]
30: Dong Wang L, Bin Yue W, Zhou Y, Wei Feng C, Liu B, Zhou Q, Ying Jia Y, Zheng S, Gao SS, Ji Xie X, Min Fan Z, Min Niou H, Hao Zhuang Z, Yang CS, Min Bai Y, Jun Qi Y. Related Articles, Links
Endoscopic screening and determination of p53 and proliferating cell nuclear antigen in esophageal multistage carcinogenesis: a comparative study between high- and low-risk populations in Henan, northern China.
Dis Esophagus. 2002;15(1):80-4.
PMID: 12060048 [PubMed - indexed for MEDLINE]
31: Zhou Q, Dong Wang L, Du F, Zhou Y, Rui Zhang Y, Liu B, Wei Feng C, Gao SS, Fan ZM, Yang CS, Zheng S. Related Articles, Links
Changes of TGFbeta1 and TGFbetaRII expression in esophageal precancerous and cancerous lesions: a study of a high-risk population in Henan, northern China.
Dis Esophagus. 2002;15(1):74-9.
PMID: 12060047 [PubMed - indexed for MEDLINE]
32: Chen H, Wang LD, Guo M, Gao SG, Guo HQ, Fan ZM, Li JL. Related Articles, Links
Alterations of p53 and PCNA in cancer and adjacent tissues from concurrent carcinomas of the esophagus and gastric cardia in the same patient in Linzhou, a high incidence area for esophageal cancer in northern China.
World J Gastroenterol. 2003 Jan;9(1):16-21.
PMID: 12508343 [PubMed - indexed for MEDLINE]
33: Si HX, Tsao SW, Poon CS, Wang LD, Wong YC, Cheung AL. Related Articles, Links
Viral load of HPV in esophageal squamous cell carcinoma.
Int J Cancer. 2003 Feb 10;103(4):496-500.
PMID: 12478665 [PubMed - indexed for MEDLINE]
34: Wang LD, Liu B, Zheng S. Related Articles, Links
[Analysis of p53 mutational spectra of esophageal squamous cell carcinomas from Linzhou, comparison with esophageal and other cancers from other areas]
Zhonghua Liu Xing Bing Xue Za Zhi. 2003 Mar;24(3):202-5. Chinese.
PMID: 12816712 [PubMed - in process]
35: Hara Y, Zheng Z, Evans SC, Malatjalian D, Riddell DC, Guernsey DL, Wang LD, Riabowol K, Casson AG. Related Articles, Links
ING1 and p53 tumor suppressor gene alterations in adenocarcinomas of the esophagogastric junction.
Cancer Lett. 2003 Mar 20;192(1):109-16.
PMID: 12637159 [PubMed - indexed for MEDLINE]
36: Song ZB, Gao SS, Yi XN, Li YJ, Wang QM, Zhuang ZH, Wang LD. Related Articles, Links
Expression of MUC1 in esophageal squamous-cell carcinoma and its relationship with prognosis of patients from Linzhou city, a high incidence area of northern China.
World J Gastroenterol. 2003 Mar;9(3):404-7.
PMID: 12632485 [PubMed - indexed for MEDLINE]
37: Wang LD, Zheng S, Zheng ZY, Casson AG. Related Articles, Links
Primary adenocarcinomas of lower esophagus, esophagogastric junction and gastric cardia: in special reference to China.
World J Gastroenterol. 2003 Jun;9(6):1156-64. Review.
PMID: 12800215 [PubMed - indexed for MEDLINE]
38: Xing Y, Ning Y, Ru LQ, Wang LD. Related Articles, Links
Expressions of PCNA, p53, p21(WAF-1) and cell proliferation in fetal esophageal epithelia: comparative study with adult esophageal lesions from subjects at high-incidence area for esophageal cancer in Henan, North China.
World J Gastroenterol. 2003 Jul;9(7):1601-3.
PMID: 12854173 [PubMed - indexed for MEDLINE]
39: Wang LD, Zheng S, Liu B, Zhou JX, Li YJ, Li JX. Related Articles, Links
CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China.
World J Gastroenterol. 2003 Jul;9(7):1394-7.
PMID: 12854128 [PubMed - indexed for MEDLINE]
40: Zhuang ZH, Wang LD, Tsao SW, Cheung LM, Feng HC, Yang T, Qin YR, Wang CD, Chen ZZ, Liu B. Related Articles, Links
[Cyclooxygenase-2 expression in esophageal cancer cells and induction by mitomycin C]
Zhonghua Nei Ke Za Zhi. 2003 Oct;42(10):701-4. Chinese.
PMID: 14633464 [PubMed - indexed for MEDLINE]
41:
Wang Y, Fang MZ, Liao J, Yang GY, Nie Y, Song Y, So C, Xu X, Wang LD, Yang CS.

Related Articles, Links
Free Full Text Hypermethylation-associated inactivation of retinoic acid receptor beta in human esophageal squamous cell carcinoma.
Clin Cancer Res. 2003; 1; 9(14):5257-63.
PMID: 14614007 [PubMed - indexed for MEDLINE]
42: So CK, Nie Y, Song Y, Yang GY, Chen S, Wei C, Wang LD, Doggett NA, Yang CS. Related Articles, Links
Loss of heterozygosity and internal tandem duplication mutations of the CBP gene are frequent events in human esophageal squamous cell carcinoma.
Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):19-27.
PMID: 14734447 [PubMed - indexed for MEDLINE]
43: Fang MZ, Liu C, Song Y, Yang GY, Nie Y, Liao J, Zhao X, Shimada Y, Wang LD, Yang CS. Related Articles, Links
Overexpression of gastrin-releasing peptide in human esophageal squamous cell carcinomas.
Carcinogenesis. 2004 Feb 4 [Epub ahead of print]
PMID: 14764456 [PubMed - as supplied by publisher]
44: Deng W, Tsao SW, Guan XY, Lucas JN, Si HX, Leung CS, Mak P, Wang LD, Cheung AL. Related Articles, Links
Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines.
Oncogene. 2004; 23(56): 9090-9101.[Epub ahead of print]
PMID: 15489894 [PubMed - as supplied by publisher]
45: An JY, Fan ZM, Zhuang ZH, Qin YR, Gao SS, Li JL, Wang LD. Related Articles, Links
Proteomic analysis of blood level of proteins before and after operation in patients with esophageal squamous cell carcinoma at high-incidence area in Henan Province.
World J Gastroenterol. 2004 Nov 15;10(22):3365-8.
PMID: 15484320 [PubMed - in process]
46: Qin YR, Wang LD, Kwong D, Guan XY, Zhuang ZH, Fan ZM, An JY, Tsao G. Related Articles, Links
[Comparative genomic hybridization of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma in high-incidence region of esophageal carcinoma, Linzhou Henan.]
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004 Dec;21(6):625-8. Chinese.
PMID: 15583998 [PubMed - in process]
47: Qin YR, Wang LD, Kwong D, Gao SS, Guan XY, Zhuang ZH, Fan ZM, Deng W, Hu L. Related Articles, Links
[Comparative genomic hybridization: the profile of chromosomal imbalances in esophageal squamous cell carcinoma.]
Zhonghua Bing Li Xue Za Zhi. 2005 Feb;34(2):80-3. Chinese.
PMID: 15842801 [PubMed - in process
48: Fang MZ, Jin Z, Wang Y, Liao J, Yang GY, Wang LD, Yang CS. Related Articles, Links
Promoter hypermethylation and inactivation of O6-methylguanine-DNA methyltransferase in esophageal squamous cell carcinomas and its reactivation in cell lines.
Int J Oncol. 2005 Mar;26(3):615-22.
PMID: 15703815 [PubMed - in process]
49: An JY, Fan ZM, Gao SS, Zhuang ZH, Qin YR, Li JL, He X, Tsao GS, Wang LD. Related Articles, Links
Loss of heterozygosity in multistage carcinogenesis of esophageal carcinoma at high-incidence area in Henan Province, China.
World J Gastroenterol. 2005 Apr 14;11(14):2055-60.
PMID: 15810068 [PubMed - in process]
50: Qi Y, Chiu JF, Wang L, Kwong DL, He QY. Related Articles, Links
Comparative proteomic analysis of esophageal squamous cell carcinoma.
Proteomics. 2005 Jul;5(11):2960-71.
PMID: 15986332 [PubMed - in process]
51: Wang DC, Wang LD, Zheng S, Fan ZM, Li JL, Feng CW, Zhang YR, Liu B, Gao SS, He X. Related Articles, Links
[The application of surface-enhanced laser desorption/inionation-time of flight-mass spectrometry in diagnosing dysplasia and chronic atrophic gastric-carditis in population with high risk of gastric-cardia adenocarcinoma.]
Zhonghua Nei Ke Za Zhi. 2005 Aug;44(8):573-6. Chinese.
PMID: 16194406 [PubMed - in process]
52: Wang LD, Yang HH, Fan ZM, Lu XD, Wang JK, Liu XL, Sun Z, Jiang YN, He X, Zhou Q. Related Articles,